(Empty Backbone) pDONR split marker vector (GenBank accession number: KX904529) for fungal gene deletion. Used with pSM1.

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Please accept our privacy terms We use cookies and similar technologies to improve your browsing experience, personalize content and offers, show targeted ads, analyze traffic, and better understand you. We may share your information with third-party partners for marketing purposes. To learn more and make choices about data use, visit our. By clicking “Accept and Continue” below, (1) you consent to these activities unless and until you withdraw your consent using our rights request form, and (2) you consent to allow your data to be transferred, processed, and stored in the United States. • • • • • • Back pain is a common reason for absence from work and for seeking medical treatment. It can be uncomfortable and debilitating.

It can result from injury, activity and some medical conditions. Back pain can affect people of any age, for different reasons. As people get older, the lower back pain increases, due to factors such as previous occupation and degenerative disk disease.

Lower back pain may be linked to the bony lumbar spine, discs between the vertebrae, ligaments around the spine and discs, spinal cord and nerves, lower back muscles, abdominal and pelvic internal organs, and the skin around the lumbar area. Pain in the upper back may be due to disorders of the aorta, tumors in the chest, and spine. Problems with the spine such as osteoporosis can lead to back pain. The human back is composed of a complex structure of muscles, ligaments, tendons, disks, and bones, which work together to support the body and enable us to move around. The segments of the spine are cushioned with cartilage-like pads called disks. Problems with any of these components can lead to back pain.

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In some cases of back pain, its cause remains unclear. Damage can result from strain, medical conditions, and poor posture, among others. Strain Back pain commonly stems from strain, tension, or injury.

Frequent of back pain are: • strained muscles or ligaments • a muscle spasm • muscle tension • damaged disks • injuries,, or falls Activities that can lead to strains or spasms include: • lifting something improperly • lifting something that is too heavy • making an abrupt and awkward movement Structural problems A number of structural problems may also result in back pain. • Ruptured disks: Each vertebra in the spine is cushioned by disks. If the disk ruptures there will be more pressure on a nerve, resulting in back pain. • Bulging disks: In much the same way as ruptured disks, a bulging disk can result in more pressure on a nerve. • Sciatica: A sharp and shooting pain travels through the buttock and down the back of the leg, caused by a bulging or pressing on a nerve.